Biard, JF
1992
Program for the Automated Analysis of 2D INADEQUATE Spectra
Foster, M.P.; Mayne, C.L.; Dunkel, R.; Pugmire, R.J.; Grant, D.M.; Kornprobst, J.-M.; Verbist, J.-F.; Biard, J.-F. and Ireland, C.M.
Journal of the American Chemistry Society, 114(3):1110-1111, 1992. Funded by National Institutes of Health and US Department of Energy.
The two-dimensional structure of bistramide A (a.k.a. bistratene A) has been revised. The bis-amide polyether was isolated from a Lissoclinum sp. ascidian collected in the Fiji islands. The structure was established by a combination of modern NMR methods including 2D INADEQUATE, PS-DQF-COSY, HMQC and HMBC experiments. Critical to establishing the carbon-carbon backbone was CCBond, a new program for automated analysis of 2D INADEQUATE spectra. Bistramide A demonstrated in vitro cytotoxicity towards human colon tumor HCT-116 and murine leukemia L1210 cell lines with an IC50 of 0.1 µg/mL.
1991
The Revised Structure of Bistramide A (Bistratene A): Application of a New Program for the Automated Analysis of 2D INADEQUATE Spectra
Foster, M.P.; Mayne, C.L.; Dunkel, R.; Pugmire, R.J.; Grant, D.M.; Kornprobst, J.-M.; Verbist, J.-F.; Biard, J.-F. and Ireland, C.M.
Journal of the American Chemistry Society, 1991 (in press). Funded by National Institutes of Health and US Department of Energy.
The two-dimensional structure of bistramide A (a.k.a. bistratene A) has been revised. The bis-amide polyether was isolated from a Lissoclinum sp. ascidian collected in the Fiji islands. The structure was established by a combination of modern NMR methods including 2D INADEQUATE, PS-DQF-COSY, HMQC and HMBC experiments. Critical to establishing the carbon-carbon backbone was CCBond, a new program for automated analysis of 2D INADEQUATE spectra. Bistramide A demonstrated in vitro cytotoxicity towards human colon tumor HCT-116 and murine leukemia L1210 cell lines with an IC50 of 0.1 µg/mL.
Biard, JF
1992
Program for the Automated Analysis of 2D INADEQUATE Spectra
Foster, M.P.; Mayne, C.L.; Dunkel, R.; Pugmire, R.J.; Grant, D.M.; Kornprobst, J.-M.; Verbist, J.-F.; Biard, J.-F. and Ireland, C.M.
Journal of the American Chemistry Society, 114(3):1110-1111, 1992. Funded by National Institutes of Health and US Department of Energy.
The two-dimensional structure of bistramide A (a.k.a. bistratene A) has been revised. The bis-amide polyether was isolated from a Lissoclinum sp. ascidian collected in the Fiji islands. The structure was established by a combination of modern NMR methods including 2D INADEQUATE, PS-DQF-COSY, HMQC and HMBC experiments. Critical to establishing the carbon-carbon backbone was CCBond, a new program for automated analysis of 2D INADEQUATE spectra. Bistramide A demonstrated in vitro cytotoxicity towards human colon tumor HCT-116 and murine leukemia L1210 cell lines with an IC50 of 0.1 µg/mL.
1991
The Revised Structure of Bistramide A (Bistratene A): Application of a New Program for the Automated Analysis of 2D INADEQUATE Spectra
Foster, M.P.; Mayne, C.L.; Dunkel, R.; Pugmire, R.J.; Grant, D.M.; Kornprobst, J.-M.; Verbist, J.-F.; Biard, J.-F. and Ireland, C.M.
Journal of the American Chemistry Society, 1991 (in press). Funded by National Institutes of Health and US Department of Energy.
The two-dimensional structure of bistramide A (a.k.a. bistratene A) has been revised. The bis-amide polyether was isolated from a Lissoclinum sp. ascidian collected in the Fiji islands. The structure was established by a combination of modern NMR methods including 2D INADEQUATE, PS-DQF-COSY, HMQC and HMBC experiments. Critical to establishing the carbon-carbon backbone was CCBond, a new program for automated analysis of 2D INADEQUATE spectra. Bistramide A demonstrated in vitro cytotoxicity towards human colon tumor HCT-116 and murine leukemia L1210 cell lines with an IC50 of 0.1 µg/mL.